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Future J Pharm Sci 8(1):43 Sharma P, Tailang M (2020) Design, optimization and evaluation of buccal drug delivery system of propranolol for hypertension treatment

Treatment with A 40 oligomers significantly reduced the cell viability and apoptosis of astrocyte brain cultures and increased oxidative modifications of DNA, lipids, and protein, enhanced pro-inflammatory cytokine release and increased the activity of the proteolytic matrix metalloproteinase enzyme, matric metalloproteinase (MMP)-2 and reduced the activity of MMP-9 after 24 h

There is also evidence of RBC fragmentation (keratocytes, acanthocytes, schistocytes) in iron deficiency in dogs (Harvey et al 1982, Weiser and OGrady) and cats (Weiser and Kociba 1983)

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